From Space.com:

In 2005, Jamie Hyneman and Adam Savage, special effects experts better known by the title of their popular Discovery Channel series, “MythBusters”, were asked during an interview about the myth they would most like to test provided an unlimited budget.

“Jamie and I have done the research, and figured that the only way to end the debate about the ‘myth’ of the Apollo moon landing is to go there,” Savage replied to Slashdot, a technology news website, about the belief held by some that the United States faked the lunar landings.

Three years later, the Mythbusters are ready to share the results of their ‘trip’ as they devote their next show, airing on Wednesday, to the moon landing hoax claims.